This event caused the death of five patients.. Diethylene glycol (DEG) is an organic compound with the formula (HOCH2CH2)2O. Carbitol Wang Guiping discovered how easy it was to enter China’s pharmaceutical supply business and earn extra money. These measures quickly ended the advance of the epidemic. Jump to: navigation, search. What began as a local alert revealed a global problem in more than 30 countries and involving more than thirty brands. Soon, patients started to present anuria, acidic breathing, hepatomegaly, and unresponsiveness.  It can be a contaminant in consumer products; this has resulted in numerous epidemics of poisoning since the early 20th century. , The symptoms of poisoning typically occur in three characteristic intervals:, Fomepizole or ethanol should be quickly administered to prevent diethylene glycol being metabolized to the compound or compounds that cause the real damage.. National regulations Germany 12th Ordinance Implementing the Federal Immission Control Act - 12.BImSchV: Is not subject of the 12. Whitehouse Station, NJ: Merck & Co; 2006. DIETHYLENE GLYCOL MONOBUTYL ETHER is a ether-alcohol derivative. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. , At first, scientists thought that DEG metabolized into ethylene glycol, which is poisonous due to the metabolic production of glycolic acid, glyoxylic acid, and ultimately oxalic acid. It is supplied as a urethane grade solvent. English. skin cream and lotions, deodorants), DEG is often replaced by selected diethylene glycol ethers. The outbreak forced the government to ban the sale of paracetamol elixirs in December 1992, causing a decline of 53% in the admission of patients with kidney failure and an 84% decline in admissions by unexplained kidney failure. Low vapor pressure. It was not until September 1996 that Sinochem provided a name of the manufacturer of the tainted syrup.  The major cause of ethylene glycol toxicity is the accumulation of glycolic acid in the body, but the accumulation of calcium oxalate crystals in the kidneys can also lead to acute kidney failure. Packaging 1, 4 L in poly bottle 18 L in steel drum Legal Information Product of Dow Chemical • As a structural component of various liquid crystals. About 7% of these are Leather Auxiliary Agents, 47% are Alcohol & Hydroxybenzene & Ether, and 3% are Other Chemicals. "Counterfeit Colgate Toothpaste Found", June 14, 2007. The toothpaste was labeled as “Manufactured in South Africa” and contained misspellings like "isclinically", "SOUTH AFRLCA" and "South African Dental Assoxiation". English: Structure of Diethylene glycol monobutyl ether acetate.  On 9 January 2020, a police report indicated quantities of diethylene glycol in one brand of beer from a small upscale brewery that could have poisoned 18 people in Belo Horizonte and other cities in Minas Gerais state. Diethylene Glycol Monobutyl Ether (DB Solvent) sold by Eastman is a high boiling glycol ether used in baking enamels to promote increased flow-out and leveling in paint films. While the FDA tried to find out Tianhong’s address, Chinese officials were reluctant to become involved. The primary results revealed that the mixture was more effective than using salt alone. In July 1996, the American Embassy in China contacted Sinochem and requested a list of Chinese glycerin makers, but the company refused to reveal the names. 3053. The product was recalled and after an investigation, the Drug Controller General of India, VG Somani, said at India Pharma 2020, that the GMP was not followed, and negligence was found during the production process itself. Seventeen other persons have also been charged related to this incident. Once DEG reaches the liver, it is metabolized by enzymes. in textile processing and serves as an intermediary product in the chemical industry.  Spanish authorities are prosecuting Asunción Criado, general manager of Rasfer Internacional, S.A., and await Panamanian citizens, René Luciani (former Social Security Director) and Jéssica Rodríguez (former Purchase National Director) for their hearings. Features. , A propolis syrup manufactured by Huilen Laboratories in Buenos Aires, Argentina, contained between 24 and 66.5% DEG, and caused the death of 29 people. ", "Scandal over poisoned wine embitters village in Austria.". , Taixing sold the syrup as “TD glycerin”, wording that neither Chinese inspectors nor Spanish medical authorities comprehended. Most ethylene glycol antifreeze contains a few percent diethylene glycol, present as an byproduct of ethylene glycol production. Butyl di glycol (also known as BDG, butyl dioxitol, diethylene glycol monobutyl ether, 2(-2butoxyethoxy) ethanol and butoxydiethylene glycol) is a colourless, clear organic compound with a faint characteristic odour that has the formula C 8 H 18 O 3.It is soluble in water and miscible with many common solvents, and also has low volatility and a high boiling point. Jean-Claude Bradley Open Melting Point Dataset, NFPA 704: Standard System for the Identification of the Hazards of Materials for Emergency Response, InChI=1S/C8H18O3/c1-2-3-5-10-7-8-11-6-4-9/h9H,2-8H2,1H3, Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard, splash10-006t-9000000000-9b5ce4bf5bfa84239e88, splash10-03di-1900000000-8aef03e0bb456b96d1a4, splash10-03di-0900000000-3ac8a328666dee650638, splash10-0a4j-9000000000-44b0731c3639435643fb, https://www.wikidata.org/w/index.php?title=Q1018210&oldid=1314798026, Creative Commons Attribution-ShareAlike License. Besides Wang, five employees of Qiquihar were prosecuted. Further investigation revealed all patients were treated with topical silver sulfadiazine ointment that contained 7 g/kg of DEG. , In Cape Town, South Africa, seven children developed vomiting, diarrhea, and dehydration, and died of kidney failure after administration of over-the-counter sedatives. Soon, patients from other parts of the country started to arrive at hospitals. Wang declared that after making the first order of counterfeit syrup, he swallowed some of it. stated in. During September 1986, the Ministry of Public Works started testing a mixture of wine with salt to melt hazardous ice during winter.  The United States Food and Drug Administration also issued an Industry Guidance Document “intended to alert pharmaceutical manufacturers, pharmacy compounders, repackers, and suppliers to the potential public health hazard of glycerin contaminated with diethylene glycol (DEG)” and recommended appropriate testing procedures for the use of glycerin. Once physicians identified a suspect paracetamol syrup, samples were shipped to the Centers for Disease Control and Prevention (CDC) in the U.S., which identified DEG. Date: 27 January 2011: Source: Own work: Author: MiPe: Licensing . The ether being relatively unreactive. , At a hospital in Bombay, India, patients were admitted to be treated for diverse health problems. diethylene glycol monobutyl ether (English) retrieved. , Ending September 2006, the Arnulfo Arias Madrid Hospital at Panama City was getting full with patients with contradictory symptoms. Panama awaits the extradition of Criado for her hearing. , In the first week of 2020, around 17 children from Ramnagar, in the union territory of Jammu and Kashmir, were hospitalised, more than half of whom died of kidney failure. 9TB90IYC0E. , In December 2019, some people in the city of Belo Horizonte, initially all from the same neighbourhood, started having symptoms such as nausea, vomiting, abdominal pain, acute kidney failure, facial nerve paralysis, blurred vision, temporary blindness and sensory changes. The OEL or MAK value for diethylene glycol monobutyl ether is 67 mg/m 3 (10 ppm) [1, 2]. Meanwhile, in Panama, De la Cruz, legal representative of Medicom, remains in jail pending a trial. FDA Detains One Contaminated Shipment, Issues Import Alert", June 1, 2007. Bogdanich, W. "Toxic Toothpaste Made in China Is Found in U.S. ". A dilute solution of diethylene glycol can also be used as a cryoprotectant; however, ethylene glycol is much more commonly used. 14th ed. Promotes uniform dispersion; translucent to clear. , On June 1, 2007, the FDA warned consumers to avoid toothpaste from China, although there was no information if these toothpastes had already entered the US, and started testing any imported Chinese toothpaste. For late diagnosis where ethanol or fomepizole is ineffective, because DEG has already been metabolized, hemodialysis becomes the only treatment available. Record Status: Validated (UNII) … CAS Number 111-76-2 Synonym(s) EGBE, AI-0993; Bucs; Butoxyethanol; Beta-butoxyethanol; 2-Butoxyethanol; 2-butoxy-1-ethanol; Butyl cellosolve; o-butyl ethylene glycol; Butyl glycol; Butyl oxitol; Caswell No. The CDC employed modern laboratory equipment to analyze the samples and confirm the results: the samples contained approximately 8% v/v DEG. O’Neil M. The Merck Index. Doctors had no idea what was happening: the mysterious illness was attacking elderly citizens with hypertension and diabetes history. In November, The New York Times published a wine recall that the Federal Government released after the Bureau of Alcohol, Tobacco and Firearms tested 1,000 bottles. , In the poorest country in the Western Hemisphere, disease outbreaks are not recognized unless widespread or unusual. Shortly after, 2-hydroxyethoxyacetaldehyde (C4H8O3) is metabolized by the enzyme aldehyde dehydrogenase (ALDH) into the weak acid 2-hydroxyethoxyacetic acid (HEAA) with chemical formula C4H8O4. A wide variety of diethylene glycol monobutyl ether options are available to you, such as classification, grade standard, and usage. The death rate of this mysterious illness was nearly 50%, when hospital management decided to isolate all the patients with the illness in a large room and doctors could compare notes and theories. , Panama’s case made CDC set standardized methodology for DEG identification, hoping to have more timely response in future events.  Two months later, findings revealed that 145 were proven to die by DEG intoxication, but the DA still has to investigate 953 demands.  Immediately, biological samples and the syrup were sent by jet to CDC for analysis. Nearly half of the victims were under the age of two. Internal Medicine Residency Program of the College of Medicine of Wake Forest University, North Caroline, U.S.A. Acute Renal Failure Investigation Team", "Fatal renal failure caused by diethylene glycol in paracetamol elixir: the Bangladesh epidemic", "Identification and Quantification of Diethylene Glycol in Pharmaceuticals Implicated in Poisoning Epidemics: An Historical Laboratory Perspective", "F.D.A.  As a result of the case-control findings, and subsequent investigation at the factory, public warnings were issued by the Ministry of Health and bottles of the two medications were taken from pharmacy shelves and destroyed. Postmortem examination revealed damage in the kidneys and liver, and laboratory testing found DEG instead of propylene glycol in the sedatives.  The investigation revealed that DEG had been used as a coolant for the brewery equipment, in what should have been a closed circuit, but an undetected leak in the system contaminated some batches of beer.  On 17 January, the police confirmed the fourth death from symptoms matching DEG poisoning, and DEG contamination had been found in eight brands of beer from the same brewery. The agency also identified urinary DEG as a biomarker for DEG exposures. Eastman™ DE Acetate (Diethylene Glycol Monoethyl Ether Acetate) is a colorless liquid, soluble in water and miscible in most organic solvents. , InChI=1S/C4H10O3/c5-1-3-7-4-2-6/h5-6H,1-4H2, InChI=1/C4H10O3/c5-1-3-7-4-2-6/h5-6H,1-4H2, Except where otherwise noted, data are given for materials in their, 1937 – The Massengill Incident (United States). 17 November 2016. All structured data from the main, Property, Lexeme, and EntitySchema namespaces is available under the. The ether being relatively unreactive.  For the end of the month, the Chinese government committed to investigate the “supposedly” tainted toothpaste that had been recalled in Panama and Dominican Republic, but stated that, as per an essay written in 2000, a toothpaste containing 15.6% was not dangerous. Bureau of Alcohol, Tobacco, and Firearms. In fact, the company bought the product in China and had already re-exported toothpaste to Costa Rica, Dominican Republic and Haiti, making Panama kick off a local warning.  This episode was the impetus for the Federal Food, Drug, and Cosmetic Act of 1938. The study revealed a strong association between ingestion of two locally produced acetaminophen liquid products (Afebril and Valodon) and illness. Hemodialysis might be administered alone or with ethanol or fomepizole. It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. , In August 2009, the Supreme Court decided to send the diethylene glycol file to the Public Ministry for an extension. BlmSchV (Hazardous Incident Ordinance) It is a humectant for tobacco, cork, printing ink, and glue. Diethylene Glycol Monobutyl Ether poisoning symptoms, causes, diagnosis, and treatment information for Diethylene Glycol Monobutyl Ether poisoning (Chemical poisoning - Diethylene Glycol Monobutyl Ether) with alternative diagnoses, full-text book chapters, misdiagnosis, research … 2-(2-Ethoxyethoxy)ethanol (IUPAC) Diethylene Glycol Monoethyl Ether. This page was last edited on 28 November 2020, at 22:06. Rat models suggest DEG is metabolized in the liver by enzyme NAD-dependent alcohol dehydrogenase (ADH) into a hydrogen ion, NADH and 2-hydroxyethoxyacetaldehyde (C4H8O3). DIETHYLENE GLYCOL MONOBUTYL ETHER For Synthesis is not on the REACH Candidate List DIETHYLENE GLYCOL MONOBUTYL ETHER For Synthesis is not on the REACH Annex XIV List 15.1.2. Massengill Co. (a Tennessee drug company), manufactured sulfanilamide dissolved with diethylene glycol, to create a liquid alternative of this drug. Ethylene glycol is by far the largest volume of the glycol products in a variety of applications. Diethylene glycol monobutyl ether.  In Spain, Rasfer International declared bankruptcy after the lawyer of Medicom filed a lawsuit of $400 million in July 2008. The factory of the medication manufacturer, Pharval, was subsequently investigated by Dr. Joel Selanikio (also of CDC, and an Epidemic Intelligence Service classmate of Katherine O'Brien). Draw with ChemBioDraw Ultra 12.0. Diethylene glycol monobutyl ether (DEGBE) is used: • In the preparation of blocked isocyanate systems for coil coating, electro-coating and powder coating. They also arrested 12 people in connection with the incident. Panamanian officials traced the toothpaste to a local company in the Colón Free Trade Zone. It is used primarily as a coalescing aid in latex paints and as a solvent in printing inks. Diethylene Glycol Ether Factory Offer High Grade 99% Butyldiglycol/ Diethylene Glycol Monobutyl Ether Cas 112-34-5 US $2.00-$5.00 / Kilogram 1.0 Kilograms (Min Order) * *  DEG is a widely used solvent. Diethylene glycol monobutyl ether is used as a solvent in paints and varnishes e.g. Alibaba.com offers 101 diethylene glycol monobutyl ether products. About half were receiving Lisinopril (a blood pressure medicine), and many did not remember clearly if they had been taking other drugs. The episode resulted in the deaths of 21 patients and the discovery of glycerin contaminated with 18.5% v/v of DEG. Dermal absorption is very low, unless it is administered on broken or damaged skin.  Soon, other countries also recalling Chinese-made toothpaste were Belize, Canada, Mozambique, Saudi Arabia, New Zealand, Spain, Italy, Japan, and Ireland, plus an Indianapolis, Indiana US hotel-supplier that distributed Chinese toothpaste in Barbados, Belgium, Bermuda, Britain, Canada, Dominican Republic, France, Germany, Ireland, Italy, Mexico, Spain, Switzerland, Turks and Caicos, the United Arab Emirates and United States. After manufacturing a second batch of syrup containing diethylene glycol for Qiquhar Pharmaceutical, no taste-test was performed. Our team of experts are at the ready. , Based on available literature, scientists suggest unmetabolized DEG and HEAA are partially reabsorbed through glomerular filtration.  Although there were no reports of anyone harmed, several people in the eastern US reported experiencing headaches and pain after using the product. Doctors prescribed glycerine for its osmotic diuretic effect, but patients started to develop kidney failure.  On 9 June, the police indicted 11 people, including brewery owners and employees, for manslaughter, unintentional bodily harm and food contamination. Although there is limited information about toxicokinetics in humans, observations in mass poisonings and experimental studies suggest the following information: The principal method of absorption is through oral ingestion. Chemical Nomenclature. Later, raw glycerin was analyzed and results revealed 22.2% v/v DEG. It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. Once he was inside, there was nothing to do: the plant had already been shut down. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. DIETHYLENE GLYCOL MONOBUTYL ETHER 9TB90IYC0E Overview Structure Names 9: Classification 1: Identifiers 9: Relationships 1: Active Moiety 1: Audit Info References 15: Moieties 1: Substance Class: Chemical Record UNII: 9TB90IYC0E. The company tested the new product, Elixir Sulfanilamide, for viscosity, appearance and fragrance. It was assumed that DEG was used as a substitute of propylene glycol, and this incident encouraged the Nigerian government to develop pharmaceutical quality control guidelines. language of work or name. Fourteen patients received hemodialysis, but the treatment failed. In April 2006, the Guangdong Province Hospital of Guangzhou began administering Amillarisin A to their patients. Diethylene glycol is one of several glycols derived from ethylene oxide. , The Panamanian Government made a nationwide campaign, collecting around 6,000 bottles of cough syrup and three other products with the tainted glycerin manufactured by Social Security Laboratories.  By June 1996, with no idea what was causing the epidemic, the Pan American Health Organization (PAHO) Haiti representative contacted the World Health Organization (WHO, the parent agency of PAHO), and WHO requested that the Centers for Disease Control and Prevention investigate.. Diethylene Glycol Monobutyl Ether Acetate Market is a professional and a complete report focusing on primary and secondary drivers, market share, competitor analysis, leading segments and geographical analysis. Bogdanich, W.; McLean, R. "Poisoned Toothpaste in Panama Is Believed to Be From China". Incidents include its use in China as a component of cheap toothpaste, and by winemakers in Europe as an adulterant to create a "sweet" wine. Tracked Poisoned Drugs, but Trail Went Cold in China", "From China to Panama, a trail of Poisoned Medicine", "Aumentan Envenenados con Dietilene Glycol", "Outbreak of acute renal failure in Panama in 2006: a case-control study", "Caso dietilene glycol puede viciarse: Troitiño", "24 Niños afectados por utilización de tóxico", "Rasfer Internacional se declara en bancarrota", "Panamá bloquea el proceso español por el caso del jarabe asesino", Guidance for Industry – Testing of Glycerin for Diethylene Glycol, "China investigating toothpaste containing potentially deadly chemical", "U.S. checking all toothpaste imports from China", "7online.com: Toothpaste recall expands 6/18/07", "The Everyman Who Exposed Tainted Toothpaste", News.yahoo.com Nigeria child deaths from tainted syrup rise to 84, Nigeria child deaths from tainted syrup rise to 84, "84 Children Are Killed by Medicine in Nigeria", NAFDAC Negotiates State of the art Anti Counterfeiting Equipment, "Laudo da Polícia Civil aponta que cerveja adulterada causou doença misteriosa em BH", "Polícia confirma 3ª morte por síndrome nefroneural", "Ministério da Agricultura identifica contaminação em oito rótulos de cervejas da Backer", "Morre 10ª vítima por intoxicação de cerveja da Backer", "Behind killer cough syrup Coldbest: Glaring gaps in regulation and its manufacture", "J&K children deaths: Kids consumed cough syrup with poisonous chemical, probe reveals", https://en.wikipedia.org/w/index.php?title=Diethylene_glycol&oldid=998487761, Articles with dead external links from July 2019, Articles with permanently dead external links, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Articles containing Chinese-language text, Creative Commons Attribution-ShareAlike License, 244 to 245 °C (471 to 473 °F; 517 to 518 K), This page was last edited on 5 January 2021, at 16:24. U.S. Food and Drug Administration Press Release. Details : Ethylene Glycol Monobutyl Ether. title. The industry generally operates to maximize MEG production. It is a solvent for nitrocellulose, resins, dyes, oils, and other organic compounds. The poison had caused the death of at least 84 Nigerian children between ages of two months and seven years. Availability of DEG will depend on demand for derivatives of the primary product, ethylene glycol, rather than on DEG market requirements.". Synonyms and Related Terms. CS1 maint: multiple names: authors list (. All patients are likely to suffer significant morbidity. A series of solvents used for oils, resins, gums and many polymers that is sold commercially under the name Carbitol. The difference between ethylene glycol and diethylene glycol is that an ethylene glycol molecule is an individual molecule whereas diethylene glycol molecule is formed by the combination of two ethylene glycol molecules via an ether bond. Later on, HEAA leaves the liver through the bloodstream, being partially filtered in the kidneys for elimination. Unique Ingredient Identifier.  The world outcry made Chinese officials ban the practice of using diethylene glycol in toothpaste. , In 1937, S.E.  On 18 July, the 10th victim died in a Belo Horizonte hospital, a 65-year-old man who had been hospitalized since December 2019 due to the poisoning.  The 46 barrels of syrup were bought by Social Security Laboratories through a Panamanian middleman, Grupo Comercial Medicom, who bought the product from Rasfer Internacional, a Spanish company. , DEG is produced by the partial hydrolysis of ethylene oxide. Some wines contained less than 10 parts per million of DEG, a small amount that could not be detected by laboratory analysis in Europe. Fill out the form below and we will be in touch shortly. High boiling point. The risk assessment is based mainly on open scientific literature and on skin absorptions studies done by Industry. Records also revealed that to fool buyers, Wang falsified his license and laboratory analysis reports.  In personal care products (e.g. BACKGROUND A risk assessment of DEGBE with the chemical name 2-(2-butoxyethoxy)ethanol or diethylene glycol monobutyl ether was done by a member state (France). Some time later, Wang found a reference to diethylene glycol in a chemical book. , After recalling millions of wine bottles, the Austrian Government had no idea how to destroy the product. They identified Tianhong Fine Chemicals Factory as the manufacturer. Only 88 children deaths were recalled by doctors or had medical records. Investigations revealed that all had taken a medicine called “My Pikin Baby”, a teething mixture tainted with diethylene glycol. This product is created when ethylene oxide and n-butanol are combined.  The following month, the Toxicology Department of the Institute of Legal Medicine and Forensic Science published a list of 1,155 names whose medicine bottles tested positive for DEG. More commonly known as Diethylene Glycol Monoethyl Ether. When 105 people died in 15 states during the months of September and October, the trail led back to the elixir, and the toxic potential of this chemical was revealed. Diethylene glycol is used in the manufacture of saturated and unsaturated polyester resins, polyurethanes, and plasticizers. What is Diethylene Glycol Monobutyl Ether? Vos records revealed the syrup had been bought from Sinochem International Chemicals Company through a German trader, Metall-Chemie. U.S. Food and Drug Administration Press Release. The symptoms seemed to match with Guillain–Barré syndrome, but these patients were also losing their ability to urinate, a symptom not related to Guillain–Barré. It is also used in printing inks when very slow drying is desired. Industry Circular No. I, the copyright holder of this work, hereby publish it under the following licenses: , In Bangladesh between 1990 and 1992, 339 children developed kidney failure, and most of them died, after being given paracetamol (acetaminophen) syrup contaminated with diethylene glycol. 0 references.  Days later, Colgate-Palmolive found counterfeit toothpaste with its name, which was contaminated with DEG and found at dollar-type discount stores in New York, New Jersey, Pennsylvania and Maryland. Unfortunately, Taixing used “TD” for the Chinese word tidai, meaning “substitute”.  Once verifying that he was fine, he shipped it to Qiquihar No. 2-(2-Butoxyethoxy)acetic acid was the major urinary metabolite with about 53% to … Barewa Pharmaceuticals was shut down and the product was pulled off the shelves. The LD50 for small mammals has been tested at between 2 and 25 g/kg, less toxic than its relative ethylene glycol, but still capable of causing toxicity in humans. Authorities warn against using some toothpastes, Taste of Raspberries, Taste of Death – The 1937 Elixir Sulfanilamide Incident, "Wallace Reveals How Federal Agents Traced Elixir to Halt Fatalities", "Medication-associated diethylene glycol mass poisoning: A review and discussion on the origin of contamination", "Popular Wines found to hold toxic chemical. Diethylene glycol, monobutyl ether Ethyl Digol Glycol Ether DM ETHANOL, 2-(2-ETHOXYETHOXY)-DEGME. , The Nigerian government traced the diethylene glycol to an unlicensed chemical dealer in Lagos, who sold it to a local pharmaceutical manufacturer. , Ending November 2008, infants started to die after developing unexplained fevers and vomiting. 9TB90IYC0E. UNII. The fiscal attorney urged affected citizens to approach the Public Ministry to update the official legal file and for further medical analysis. Diethylene glycol monobutyl ether Valid: TSCA Inv Ethanol, 2-(2-butoxyethoxy)- Valid: CAA 111 Diethylene glycol monobutyl ether Valid: 01/05/1981: CAA112(b) HAP Diethylene Glycol Monobutyl Ether Unknown: Pesticide Tolerance Exemptions Diethylene glycol mono butyl ether Unknown Regulations in Austria. ``, S.E a mixture of wine with salt to melt hazardous during! Partially reabsorbed through glomerular filtration Toothpaste to a local company in the chemical industry reaction! Ointment that contained 7 g/kg of DEG sulfadiazine ointment that contained 7 g/kg of.! Glycol or propylene glycol commonly used in paints and cleaners Fine, he swallowed some it... He shipped it to Qiquihar no, ethylene glycol is by far the volume. They were prescribed an expectorant glycerin was analyzed and results revealed that the mixture was more effective than using alone. 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